Role of TMPRSS6 rs855791 (T > C) polymorphism with iron and ferritin in Iraqi adult patients with iron deficiency anemia
نویسندگان
چکیده
Our study aimed to investigate the association between TMPRSS6 polymorphism and risk of iron deficiency anemia. In this analytical (case control) study, venous blood samples were taken from (100) subjects, (50) patients with anemia healthy volunteers as a control group. Hemoglobin (Hb), mean corpuscular volume (MCV), hemoglobin concentration (MCHC), (MCH), iron, ferritin measured. Genomic DNA was extracted by salting out method C/T AQP1 analyzed using polymerase chain reaction (PCR). The results showed that frequency TT genotype higher in IDA patients. also significantly low Hb concentration, MCV, MCHC, MCH, when compared normal individuals (P≤0.00). well gene mutant within shown have no interaction CBC parameters (Hb, MCH RBC). comparison controls. conclusion, there statistically significant same AQP1gene among Iraqi Baghdad state. Also, There interactions observed genotypes means Hb, group individuals. But differences
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TMPRSS6 rs855791 Polymorphism Influences the Susceptibility to Iron Deficiency Anemia in Women at Reproductive Age
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ژورنال
عنوان ژورنال: BIO web of conferences
سال: 2023
ISSN: ['2273-1709', '2117-4458']
DOI: https://doi.org/10.1051/bioconf/20236507009